Infections of the Lymphatic System

However, in many infections the effect on the lymphatics may be both consistent and clinically marked. The lymphadenopathy may be local or generalized and lymphadenopathy is or can be a significant feature of acute HIV infection, primary Herpes simplex, some rickettsial infections, tularaemia, plague, cat-scratch fever due to Bartonella henselae, primary syphilis, lymphogranuloma venereum, chancroid, leptospirosis, brucellosis, relapsing fever, African trypanosomiasis (e.g. Winterbottom’s Sign), Chagas’ disease, and leishmaniasis. Charters 3 also lists schistosomiasis (during the Katayama phase), paragonimiasis, onchocerciasis, trichinosis, leprosy, and sporotrichosis as causes of lymphadenopathy. However, the most significant and noteworthy involvement of the lymphatic system is seen in the Glandular Fever Syndrome and in Lymphatic filariasis. It is these two conditions, which will be dealt with in detail.